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Harvey, 1628

How We Found Out Blood Goes Round

The old idea was that blood is made and used up. One piece of arithmetic destroyed it.

The old idea Blood is made in theliver and consumedWhat the arithmeticshowed The same blood goesround and round
Nobody had multiplied it out. That was the entire discovery.
  1. Step 1 of 5

    For 1,400 years, blood was thought to be used up.

    1 Food becomesblood in theliver2 The bodyconsumes it3 It is used upand replaced

    The accepted picture was that the liver made blood from food, the body consumed it like fuel, and more was made. It was detailed, internally consistent, taught everywhere, and completely wrong.

  2. Step 2 of 5

    Harvey measured how much the heart holds.

    One heart About 60 ml pushed outper beat

    He worked on hearts from dead animals and found each beat pushes out a couple of tablespoons. That is a small, unremarkable number, and nobody had thought it worth combining with anything else.

  3. Step 3 of 5

    Then he multiplied by the pulse.

    Blood pumped per hourabout 250 litresBlood in the whole bodyabout 5 litres
    No liver could make that. No amount of food could supply it.

    About seventy beats a minute, sixty minutes an hour. That comes to roughly 250 litres of blood pumped every hour — around three times the weight of the whole body, every hour, all day.

  4. Step 4 of 5

    So it must be the same blood, coming back.

    Pumped out Round thebody Back through the veins And out again

    That was the only possibility left. The heart is not a factory but a pump on a loop, and the blood in it now is blood that has been round before. He confirmed it with a simple test anyone can do.

  5. Step 5 of 5

    The veins gave it away.

    One-way valves inevery vein All of them pointback to the heart

    Press a vein in your arm and slide your finger along it. It empties and stays empty until you let go — because valves inside it only allow flow one way, towards the heart. Blood in veins always travels back. It had been drawn in textbooks for years without anyone asking what one-way valves were for.

    Harvey could not see the connection between arteries and veins — capillaries are too small. They were found with a microscope thirty years later, after he died.

The short version

Circulation was proved by multiplying one heartbeat by the pulse rate: the number was far too big for blood to be made and used up.

Try it yourself

Let one hand hang down for a minute, then compare the veins on both hands. The blood pools, and you can watch a valve stop it.

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